Pamapimod-d4

SI-6364

Pamapimod-d₄, >98% (HPLC)

CAS No. : [1246814-57-2]

Synonyms : RO-4402257-d₄; R1503-d₄

IUPAC Name : 6-(2,4-Difluorophenoxy)-2-((1,5-dihydroxypentan-3-yl-1,1,5,5-d₄)amino)-8-methylpyrido[2,3-d]pyrimidin-7(8H)-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Pamapimod‑d₄ is the deuterated analog of Pamapimod, an orally active p38 MAPK inhibitor that potently and selectively targets p38α while showing minimal activity toward other p38 isoforms. Its pharmacological profile supports its use in probing p38‑driven inflammatory pathways relevant to rheumatoid arthritis and autoimmune disease models.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Hill. R. J. et al.: The Journal of pharmacology and experimental therapeutics 327, 610-619, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.