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pan‑SIK inhibitor

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SI-7495

pan‑SIK inhibitor, >98% (HPLC)

CAS No. : [3131558-08-9]

IUPAC Name : 4-(5-Bromo-1H-benzo[d]imidazol-1-yl)-2-methoxybenzamide

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Chemical Properites
Mol. Formula :
C15H12BrN3O2
Mol. Weight :
346.18
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a pan‑SIK inhibitor, targeting the salt‑inducible kinase (SIK) family with broad activity across SIK1, SIK2, and SIK3. The benzimidazole–benzamide scaffold supports strong kinase engagement, making it a useful tool compound for probing SIK‑dependent signaling pathways in inflammation, metabolism, and transcriptional regulation.

References : Temal-Laib T. et al.: J. Med. Chem., 67(1), 380-401, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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