PAR4 antagonist 1

SI-7612

PAR4 antagonist 1, >98% (HPLC)

CAS No. : [2173201-65-3]

IUPAC Name : (R)-(5-Fluoro-2-(2-methoxy-7-methylquinoxalin-5-yl)-7,8-dihydrobenzofuro[5,4-d]thiazol-7-yl)methyl (2-methylpyrimidin-5-yl)carbamate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PAR4 antagonist 1 is a highly potent protease‑activated receptor‑4 (PAR4) antagonist, showing IC₅₀ = 1.8 nM for PAR4 and IC₅₀= 2 nM against γ‑thrombin‑activated PAR4 in platelet‑rich plasma. Its strong inhibition of PAR4‑mediated platelet activation makes it a valuable tool compound for antithrombotic research and for probing PAR4‑dependent platelet signaling.

References : Zhang X. et al.: J. Med. Chem., 67(5), 3571-3589, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.