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Paricalcitol

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SL-5636

Paricalcitol, >98%

CAS No. : [131918-61-1]

Synonyms : 19-Nor-colecalciferol; 19-Nor-1-25-OH2D2; Paracalcin; Zemplar

IUPAC Name : (1R,3R)-5-(2-((1R,3aS,7aR,E)-1-((2R,5S,E)-6-Hydroxy-5,6-dimethylhept-3-en-2-yl)-7a-methyloctahydro-4H-inden-4-ylidene)ethylidene)cyclohexane-1,3-diol

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Chemical Properites
Mol. Formula :
C27H44O3
Mol. Weight :
416.65
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Paricalcitol is a selective vitamin D receptor agonist, which suppresses parathyroid hormone mRNA expression and inhibits parathyroid cell proliferation. It is used to treat secondary hyperparathyroidism in chronic kidney disease.

References : Wu-Wong J. R. et al.: Int J. Endocrinol., 621687, 2010; Cheng S. et al.: Ther Clin Risk Manag., 2(3), 297-301, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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