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Parsaclisib hydrochloride

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SI-5350

Parsaclisib hydrochloride, >98% (HPLC)

CAS No. : [1995889-48-9]

Synonyms : INCB050465 hydrochloride

IUPAC Name : (S)-4-(3-((S)-1-(4-Amino-3-methyl-1H-pyrazolo[3,4-d]pyrimidin-1-yl)ethyl)-5-chloro-2-ethoxy-6-fluorophenyl)pyrrolidin-2-one hydrochloride

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
We accept
Note: Parsaclisib hydrochlorideis not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C20H22ClFN6O2 . HCl
Mol. Weight :
469.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Parsaclisib hydrochloride is a potent, selective and orally active inhibitor of PI3Kδ, with an IC50 of 1 nM at 1 mM ATP. Parsaclisib shows approximately 20000-fold selectivity over other PI3K class I isoforms. Parsaclisib hydrochloride can be used for the research of relapsed or refractory B-cell malignancies.

References : Shin N. et al.: Cancer Research 75(15), 2671, 2015; Shin N. et al.: J. Pharmacol Exp Ther., 374(1), 211-222, 2020; Yue E. W. et al.: ACS Med Chem Lett., 10(11), 1554-1560, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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