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SI-5325

Paxalisib, >98% (HPLC)

CAS No. : [1382979-44-3]

MDL No. : MFCD30187522

Synonyms : GDC-0084; RG7666

IUPAC Name : 5-(6,6-Dimethyl-4-morpholino-8,9-dihydro-6H-[1,4]oxazino[4,3-e]purin-2-yl)pyrimidin-2-amine

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Chemical Properites
Mol. Formula :
C18H22N8O2
Mol. Weight :
382.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Paxalisib is a brain penetrant inhibitor of PI3K and mTOR with potential antineoplastic activity.

References : Heffron T. P. et al.: ACS Med Chem Lett., 7(4), 351-356, 2016; Salphati L. et al.: Drug Metab Dispos., 44(12), 1881, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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