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Pazopanib dimer

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Pazopanib dimer, >98%

CAS No. : [2095544-42-4]

IUPAC Name : 5-((4-((2,3-Dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-N-((5-((4-((2,3-dimethyl-2H-indazol-6-yl)(methyl)amino)pyrimidin-2-yl)amino)-2-methylphenyl)sulfonyl)-2-methylbenzenesulfonamide

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Chemical Properites
Mol. Formula :
C42H43N13O4S2
Mol. Weight :
858.01
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Pazopanib, which is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms. Pazopanib is an anti-cancer medication used to treat certain types of advanced kidney cancer and soft tissue sarcoma.

References : Harris P. A. et al.: J. Med. Chem., 51(15), 4632-4640, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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