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Pazopanib impurity

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Pazopanib impurity, >98%

CAS No. : [1226499-99-5]

IUPAC Name : N2,N4-Bis(2,3-dimethyl-2H-indazol-6-yl)-N4-(4-((2,3-dimethyl-2H-indazol-6-yl)amino)pyrimidin-2-yl)pyrimidine-2,4-diamine

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Chemical Properites
Mol. Formula :
C35H33N13
Mol. Weight :
635.74
Appearance :
Pale beige solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Pazopanib, which is a novel multi-target inhibitor of VEGFR1, VEGFR2, VEGFR3, PDGFR, FGFR, c-Kit and c-Fms. Pazopanib is an anti-cancer medication used to treat certain types of advanced kidney cancer and soft tissue sarcoma.

References : Harris P. A. et al.: J. Med. Chem., 51(15), 4632-4640, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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