PBD-150

SI-6637

PBD-150, >98% (HPLC)

CAS No. : [790663-33-1]

IUPAC Name : 1-(3-(1H-Imidazol-1-yl)propyl)-3-(3,4-dimethoxyphenyl)thiourea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PBD‑150 targets the Y115E/Y117E variant of human glutaminyl cyclase with nanomolar affinity (Ki = 490 nM). This selective inhibition supports its application in mechanistic studies of QC catalysis and variant‑specific activity.

References : Buchholz M. et al.: J. Med. Chem., 49(2), 664-77, 2006; DiPisa F. et al.: Acta Crystallogr F. Struct. Biol. Commun., 71(Pt 8), 986-92, 2015; Huang K. F. et al.: J. Biol. Chem., 286(14), 12439-49, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.