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PCO-371

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SI-6081

PCO-371, >98% (HPLC)

CAS No. : [1613373-33-3]

IUPAC Name : 1-(3,5-Dimethyl-4-(2-((4-oxo-2-(4-(trifluoromethoxy)phenyl)-1,3,8-triazaspiro[4.5]dec-1-en-8-yl)sulfonyl)ethyl)phenyl)-5,5-dimethylimidazolidine-2,4-dione

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C29H32F3N5O6S
Mol. Weight :
635.66
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PCO-371 acts as a full agonist of PTHR1 and shows no activity at the PTH2 receptor. As an orally active small molecule, it is useful for probing PTHR1‑dependent signaling in calcium homeostasis and bone biology.

References : Tamura T. et al.: Nat. Commun., 7, 13384, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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