PD-318088

SI-5527

PD-318088, >98% (HPLC)

CAS No. : [391210-00-7]

MDL No. : MFCD18384973

IUPAC Name : 5-Bromo-N-(2,3-dihydroxypropoxy)-3,4-difluoro-2-((2-fluoro-4-iodophenyl)amino)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PD-318088 is a potent, allosteric and non-ATP competitive MEK1/2 inhibitor, an analog of PD-184352. PD-318088 binds simultaneously with ATP in a region of the MEK1 active site that is adjacent to the ATP-binding site. This can be used for cancer research.

References : Ohren J. F. et al.: Nat Struct Mol Biol., 11(12), 1192-7, 2004; Han S. et al.: Bioorg Med Chem Lett., 15(24), 5467-73, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.