PD-407824

SI-6784

PD-407824, >98% (HPLC)

CAS No. : [622864-54-4]

IUPAC Name : 9-Hydroxy-4-phenylpyrrolo[3,4-c]carbazole-1,3(2H,6H)-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PD-407824 is a dual Chk1 and WEE1 inhibitor with IC₅₀ values of 47 nM and 97 nM, respectively. It also functions as a chemical BMP sensitizer, increasing cellular responsiveness to sub‑threshold BMP4.

References : Palmer B. D. et al.: J. Med. Chem., 49(16), 4896-911, 2006; Feng L. et al.: Cell Rep., 15(9), 2063-75, 2016; Smaill J. B. et al.: Eur. J. Med. Chem., 43(6), 1276-96, 2008; Epub 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.