PDGFR-IN-1

SI-7035

PDGFR-IN-1, >98% (HPLC)

CAS No. : [2644673-07-2]

IUPAC Name : N2-(4-(4-Ethylpiperazin-1-yl)-3-methoxyphenyl)-N4-(1H-indazol-4-yl)-5-methylpyrimidine-2,4-diamine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This compound is a potent and orally active PDGFR inhibitor, exhibiting IC₅₀ values of 2.4 nM for PDGFRα and 0.9 nM for PDGFRβ. It demonstrates strong antitumor activity with low toxicity and is suitable for investigating PDGFR‑driven osteosarcoma biology and therapeutics.

References : Chen X. et al.: J. Med Chem., 65(7), 5374-5391, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.