Pemetrexed methyl ester

SL-3747

Pemetrexed methyl ester, >98%

CAS No. : [155405-81-5]

Synonyms : Pemetrexed impurity 18

IUPAC Name : N-[4-[2-(2-Amino-4,7-dihydro-4-oxo-3H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl]benzoyl]-L-glutamic acid 1,5-dimethyl ester

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
100MG	125.00		Back Order	Estimated to ship on 04 October 2026
250MG	225.00		Back Order	Estimated to ship on 04 October 2026
1G	645.00		Back Order	Estimated to ship on 04 October 2026

Applications : Pemetrexed methyl ester is an impurity of Pemetrexed, which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).

References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res., 6(3), 1016-1023,2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.