Pemetrexed (R) enantiomer

SL-3742

Pemetrexed (R) enantiomer, >98%

CAS No. : [182009-04-7]

Synonyms : Pemetrexed EP impurity E

IUPAC Name : (R)-2-(4-(2-(2-Amino-4-oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-5-yl)ethyl)benzamido)pentanedioic acid

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25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : This is an impurity of Pemetrexed (Pemetrexed EP impurity E), which is a novel antifolate and antimetabolite for dihydrofolate reductase-thymidylate synthase (DHFR-TS). It is used to treat for pleural mesothelioma (cancer of the outer covering of the lungs) non small cell lung cancer (NSCLC).

References : Shih C. et al.: Cancer Res., 57(6), 1116-1123, 1997; Iwahori K. et al.: Int J. Cancer., 132(2), 459-471, 2013; Teicher B. A. et al.: Clin. Cancer Res., 6(3), 1016-1023, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.