Pemigatinib

SL-9730

Pemigatinib, >98%

CAS No. : [1513857-77-6]

Synonyms : INCB-054828

IUPAC Name : 3-(2,6-Difluoro-3,5-dimethoxyphenyl)-1-ethyl-8-(morpholinomethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Pemigatinib is an orally active, selective FGFR inhibitor with IC50s of 0.4 nM, 0.5 nM, 1.2 nM, 30 nM for FGFR1, FGFR2, FGFR3, FGFR4, respectively. Pemigatinib is used to treat certain types of cancer that have specific gene alterations. Also, it has the potential for cholangiocarcinoma (bile duct cancer).

References : Arudra K. et al.: J. Cutan Pathol., 45(10), 786-790, 2018; Roskoski R. Jr. et al.: Pharmacol Res., 151, 104567, 2020; Krook M. A. et al.: Cold Spring Harb Mol Case Stud., 5(4), a004002, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.