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Pemigatinib-d6

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Pemigatinib-d6, >98%

CAS No. : [2649492-49-7]

Related CAS No. : [1513857-77-6] of the unlabelled compound

Synonyms : INCB-054828-d6

IUPAC Name : 3-(2,6-Difluoro-3,5-bis(methoxy-d3)phenyl)-1-ethyl-8-(morpholinomethyl)-1,3,4,7-tetrahydro-2H-pyrrolo[3',2':5,6]pyrido[4,3-d]pyrimidin-2-one

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In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C24H21D6F2N5O4
Mol. Weight :
493.54
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Pemigatinib, which is an orally active, selective FGFR inhibitor. Pemigatinib is used to treat certain types of cancer that have specific gene alterations. Also, it has the potential for cholangiocarcinoma (bile duct cancer).

References : Arudra K. et al.: J. Cutan Pathol., 45(10), 786-790, 2018; Roskoski R. Jr. et al.: Pharmacol Res., 151, 104567, 2020; Krook M. A. et al.: Cold Spring Harb Mol Case Stud., 5(4), a004002, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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