Pemrametostat

SI-6661

Pemrametostat, >98% (HPLC)

CAS No. : [1616392-22-3]

Synonyms : GSK-3326595; EPZ-015938

IUPAC Name : (S)-6-((1-Acetylpiperidin-4-yl)amino)-N-(3-(3,4-dihydroisoquinolin-2(1H)-yl)-2-hydroxypropyl)pyrimidine-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
1G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GSK-3326595 potently inhibits PRMT5 and exhibits broad biological activity, including reduced SARS‑CoV‑2 infection, suppression of cancer‑cell growth, and induction of pro‑inflammatory macrophage polarization. It increases hepatic triglycerides without altering atherosclerosis and is a valuable tool for studying relapsed/refractory mantle cell lymphoma.

References : Che Y. et al.: Blood cancer journal, 13(1), 27, 2023; Fedoriw A. et al.: Cancer cell, 36(1), 100-114. e25, 2019; Zhang Y. et al.: Journal of Cellular and Molecular Medicine, 27(8), 1056-1068, 2023; Li Z. et al.: Journal of Medical Virology, 95(1), e28158, 2023; Luo Y. et al.: Hepatology, 74(4), 1932-1951, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.