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Pentoxifylline-d6 metabolite I

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Pentoxifylline-d6 metabolite I, >98%

CAS No. : [1185995-26-9]

Related CAS No. : [6493-06-7] of the unlabelled compound

Synonyms : rac-Lisofylline-d6; rac-Lisophylline-d6

IUPAC Name : 1-(5-Hydroxyhexyl)-3,7-bis(methyl-d3)-3,7-dihydro-1H-purine-2,6-dione

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Chemical Properites
Mol. Formula :
C13H14D6N4O3
Mol. Weight :
286.36
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version active metabolite of Pentoxifylline, which is an oral, non-selective PDE inhibitor with immune-modulating, anti-inflammatory, hemorheological, anti-fibrinolytic, and anti-proliferative effects. Pentoxifylline is used in research on peripheral vascular and cerebrovascular diseases, as well as other conditions involving impaired microcirculation.

References : Iffat H. et al.: Indian Dermatol Online J. 5(4), 510–516, 2014; Ward A. et al.: Drugs 34(1), 50-97, 1987; Castellanos-Esparza Y. C. et al.: Int. J. Oncol., 52(4), 1246-1254, 2018; Shabnam M. et al.: Iran J. Basic Med Sci., 5(50, 1083-1090, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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