PF-04217903 mesylate

SI-8042

PF-04217903 mesylate, >98% (HPLC)

CAS No. : [956906-93-7]

IUPAC Name : 2-(4-(1-(Quinolin-6-ylmethyl)-1H-[1,2,3]triazolo[4,5-b]pyrazin-6-yl)-1H-pyrazol-1-yl)ethan-1-ol methanesulfonate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PF‑04217903 mesylate is a highly potent ATP‑competitive c‑MET inhibitor (K_i= 4.8 nM) with exceptional selectivity, exceeding 1,000‑fold over 208 kinases tested. It effectively suppresses MET‑dependent signaling and demonstrates antiangiogenic activity, making it a valuable tool for investigating MET‑regulated tumor progression.

References : Timofeevski S. L. et al.: Biochemistry, 48(23), 5339-5349, 2009; Shojaei F. et al.: Cancer Res., 70(24), 10090-10100, 2010; Krumbach R. et al.: Eur. J. Cancer, 47(8), 1231-1243, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.