PF-04254644

SI-8039

PF-04254644, >98% (HPLC)

CAS No. : [959584-91-9]

IUPAC Name : (S)-6-(1-(6-(1-Methyl-1H-pyrazol-4-yl)-[1,2,4]triazolo[4,3-b]pyridazin-3-yl)ethyl)quinoline

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PF‑04254644 is an orally active c‑MET inhibitor that blocks HGF/MET signaling and has been shown to induce myocardial degeneration in rats. It is applied in studies of cardiovascular disease, cardiotoxicity, and MET‑dependent cancer models.

References : Cui J. J. et al.: J. Med. Chem., 56(17), 6651-65, 2013; Hu W. et al.: J. Appl. Toxicol., 32(12), 1008-20, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.