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PF-04856264

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SI-5384

PF-04856264, >98% (HPLC)

CAS No. : [1235397-05-3]

MDL No. : MFCD28124397

IUPAC Name : 3-Cyano-4-(2-(1-methyl-1H-pyrazol-5-yl)phenoxy)-N-(thiazol-2-yl)benzenesulfonamide

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Chemical Properites
Mol. Formula :
C20H15N5O3S2
Mol. Weight :
437.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-04856264 is a potent and selective NaV1.7 inhibitor. PF-04856264 has low potency against the rat NaV1.7 channel. PF-04856264 shows analgesic effect.

References : McCormack K. et al.: Proc Natl Acad Sci U S A 110(29), E2724-E2732, 2013; Deuis J. R. et al.: Toxins (Basel) 8(3), 78, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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