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PF-04958242

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SI-4466

PF-04958242, >98% (HPLC)

CAS No. : [1258963-59-5]

MDL No. : MFCD27987917

IUPAC Name : N-{(3S,4S)-4-[4-(5-cyano-2-thienyl)-phenoxy]tetrahydrofuran-3-yl}propane-2-sulfonamide

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Chemical Properites
Mol. Formula :
C17H19N3O4S2
Mol. Weight :
393.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-04958242 is a novel potent, selctive, and orally-active AMPA receptor (AMPAR) positive allosteric modulator (PAM) with Ki of 170 nM, EC50 of 370 nM.

References : Shaffer L. C. et al.: J. Med. Chem., 58(10), 4291-4308, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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