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PF-04979064

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SI-7172

PF-04979064, >98% (HPLC)

CAS No. : [1220699-06-8]

IUPAC Name : (S)-1-(1-(2-Hydroxypropanoyl)piperidin-4-yl)-3-methyl-8-(6-methylpyridin-3-yl)-1,3-dihydro-2H-imidazo[4,5-c][1,5]naphthyridin-2-one

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Chemical Properites
Mol. Formula :
C24H26N6O3
Mol. Weight :
446.51
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF‑04979064 selectively targets PI3Kα and mTOR with sub‑nanomolar to low‑nanomolar affinity (Ki = 0.13/1.42 nM), supporting its use in studies of PI3K/mTOR‑driven cellular signaling and oncogenic processes.

References : Cheng H. et al., ACS Med. Chem. Lett., 4(1), 91-7, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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