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PF-05089771 tosylate

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SI-5386

PF-05089771 tosylate, >98% (HPLC)

CAS No. : [1430806-04-4]

IUPAC Name : 4-(2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy)-5-chloro-2-fluoro-N-(thiazol-4-yl)benzenesulfonamide tosylate

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Chemical Properites
Mol. Formula :
C18H12Cl2FN5O3S2 . C7H8O3S
Mol. Weight :
672.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-05089771 tosylate is a potent, orally active and selective arylsulfonamide Nav1.7 inhibitor. PF 05089771 tosylate is under the study for pain and diabetic neuropathy.

References : Alexandrou A. J. et al.: PLoS One 11(4), e0152405, 2016; Theile J. W. et al.: Mol Pharmacol., 90(5), 540-548, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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