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PF-06273340

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SI-3334

PF-06273340, >98% (HPLC)

CAS No. : [1402438-74-7]

MDL No. : MFCD28902308

IUPAC Name : N-(5-(2-Amino-7-(1-hydroxy-2-methylpropan-2-yl)-7H-pyrrolo[2,3-d]pyrimidine-5-carbonyl)pyridin-3-yl)-2-(5-chloropyridin-2-yl)acetamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
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25MGRequest A Quote
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50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Note: PF-06273340is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C23H22ClN7O3
Mol. Weight :
479.92
Appearance :
Yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-06273340 is a potent and selective, orally bioavailable pan-Trk kinase inhibitor with IC50 of 6, 2, and 1 nM for Trk A, B and C, respectively.

References : Skerratt E. S. et al.: J. Med. Chem., 59(22), 10084-10099, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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