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PF-06282999

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SI-5137

PF-06282999, >98% (HPLC)

CAS No. : [1435467-37-0]

MDL No. : MFCD30533689

IUPAC Name : 2-(6-(5-Chloro-2-methoxyphenyl)-4-oxo-2-thioxo-3,4-dihydropyrimidin-1(2H)-yl)acetamide

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C13H12ClN3O3S
Mol. Weight :
325.77
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-06282999 is a potent and selective myeloperoxidase (MPO) inhibitor. It is curently in clinical trials and developing for the potential treatment of cardiovascular diseases.

References : Dong J. Q. et al.: Drug Metab Dispos. 44(2), 209-19, 2016; Ruggeri R. B. et al.: J. Med Chem., 58(21), 8513-8528, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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