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SI-7878
PF-06305591, >98% (HPLC)
CAS No. : [1449473-97-5]
IUPAC Name : (2R,3S)-3-Amino-3-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)-2-methylpropanamide
| Price And Availability | ||||
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| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C15H22N4O | Mol. Weight : 274.37 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : PF‑06305591 blocks NaV1.8 with low‑nanomolar potency (IC50 = 15 nM) and shows excellent in vitro ADME and safety properties. Its selectivity and developability make it a valuable tool compound for investigating NaV1.8‑mediated pain signaling.
References : Brown A. D. et al.: Bioorg Med. Chem., 27(1), 230-239, 2019.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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