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SI-914
PF-06685249, >98% (HPLC)
CAS No. : [1467059-70-6]
IUPAC Name : 6-Chloro-5-(6-(dimethylamino)-2-methoxypyridin-3-yl)-1H-indole-3-carboxylic acid
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | 225.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | 325.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | 525.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | 1625.00 | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | 2625.00 | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C17H16ClN3O3 | Mol. Weight : 345.78 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : PF-06685249 is a novel potent, orally active, α1β1γ1/α2β1γ1-isoform selective AMPK activator with Kd of 14 nM, EC50 of 12 nM for α1β1γ1-AMPK.
References : Edmonds J. D. et al.: J. Med. Chem., 61(6), 2372-2383, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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