PF-06747775

SI-1143

PF-06747775, >98% (HPLC)

CAS No. : [1776112-90-3]

MDL No. : MFCD29079007

IUPAC Name : N-((3R,4R)-4-Fluoro-1-(6-((3-methoxy-1-methyl-1H-pyrazol-4-yl)amino)-9-methyl-9H-purin-2-yl)pyrrolidin-3-yl)acrylamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
10MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
25MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
50MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
100MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
250MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
500MG	Request A Quote		Back Order	Estimated to ship on 01 November 2026
Note: PF-06747775 is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : A potent, selective, irreversible EGFR mutants with IC₅₀ of 12, 3, 4 and 5 nM for EGFR L858R-T790M, Del-T790M, L858R, and EGFR Del, respectively.

References : Planken S. et al.: J. Med. Chem., 60(7), 3002-3019, 2017; Patel H. et al.: Eur. J. Med Chem., S0223-5234(17), 30388-4, 2017; Wang S. et al.: J. Hematol Oncol., 9, 34,2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.