PF-06855800

SI-8103

PF-06855800, >98% (HPLC)

CAS No. : [1989620-04-3]

Synonyms : PRMT5-IN-2

IUPAC Name : (2S,3R,4S,5R)-2-(4-Amino-7H-pyrrolo[2,3-d]pyrimidin-7-yl)-5-((R)-(4-chloro-3-fluorophenyl)(hydroxy)methyl)tetrahydrofuran-3,4-diol

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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : PF‑06855800 is an orally active PRMT5 inhibitor that binds competitively with SAM and exhibits exceptional potency (K_i= 0.02 nM). Its BBB penetration and selectivity profile make it suitable for evaluating PRMT5‑dependent pathways, including those in the central nervous system.

References : Mcalpine J. I. et al.: Cancer Res., 78(13), 4857-4857, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.