PF-477736

SI-7201

PF-477736, >98% (HPLC)

CAS No. : [952021-60-2]

IUPAC Name : (R)-2-Amino-2-cyclohexyl-N-(5-(1-methyl-1H-pyrazol-4-yl)-1-oxo-2,6-dihydro-1H-[1,2]diazepino[4,5,6-cd]indol-8-yl)acetamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PF‑477736 is a potent ATP‑competitive Chk1 inhibitor (K_i= 0.49 nM) with moderate Chk2 activity and enhances Gemcitabine antitumor effects.

References : Blasina A. et al.: Mol. Cancer Ther., 7(8), 2394-404, 2008; Ashwell S. et al.: Clin. Cancer Res., 14(13), 4032-7, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.