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PF-6405761

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SI-5984

PF-6405761, >98% (HPLC)

CAS No. : [1403764-72-6]

MDL No. : MFCD22580416

Synonyms : PFI-1

IUPAC Name : 2-Methoxy-N-(3-methyl-2-oxo-1,2,3,4-tetrahydroquinazolin-7-yl)benzenesulfonamide

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Chemical Properites
Mol. Formula :
C16H17N3O4S
Mol. Weight :
347.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PF-6405761 is a highly selective an inhibitor of bromodomain and extra-terminal motif (BET) proteins.

References : Picaud S. et al.: Cancer Res.,73(11), 3336-46, 2013; Fish P. V. et al.: J. Med. Chem., 55(22), 9831-7, 2012; Cheng Z. et al.: Clin Cancer Res., 19(7), 1748-59, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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