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PG-01037 dihydrochloride

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SI-5004

PG-01037 dihydrochloride, >98% (HPLC)

CAS No. : [675599-62-9]

MDL No. : MFCD18086901

IUPAC Name : (E)-N-(4-(4-(2,3-Dichlorophenyl)piperazin-1-yl)but-2-en-1-yl)-4-(pyridin-2-yl)benzamide dihydrochloride

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Chemical Properites
Mol. Formula :
C26H26Cl2N4O . 2HCl
Mol. Weight :
554.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : PG-01037 dihydrochloride is a dopamine D3 receptor antagonist. PG 01037 dihydrochloridel is 133-fold selective for D3 over D2 receptors in vitro. It can be used for the research of cocaine addiction.

References : Higley A. E et al.: .J.Psychopharmacol., 25(2), 263−273, 2011; Grundt P. et al.: J Med Chem., 48(3), 839-48, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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