PH-797804

SI-5145

PH-797804, >98% (HPLC)

CAS No. : [586379-66-0]

MDL No. : MFCD18251426

IUPAC Name : 3-(3-Bromo-4-((2,4-difluorobenzyl)oxy)-6-methyl-2-oxopyridin-1(2H)-yl)-N,4-dimethylbenzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : PH-797804 is a ATP-competitive, selective p38α/p38β inhibitor (IC50=26 nM and Ki=5.8 nM for p38α; Ki=40 nM for p38β) and does not inhibit JNK2. PH-797804 has met safety criteria in human phase I studies and is under clinical development for several inflammatory conditions.

References : Hope H. R. et al.: J Pharmacol Exp Ther., 331(3), 882-895, 2009; Xing L. et al.: Biochemistry 48(27), 6402-6411, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.