PHA-767491 hydrochloride

SI-6389

PHA-767491 hydrochloride, >98% (HPLC)

CAS No. : [942425-68-5]

Synonyms : CAY-10572 hydrochloride

IUPAC Name : 2-(Pyridin-4-yl)-1,5,6,7-tetrahydro-4H-pyrrolo[3,2-c]pyridin-4-one;hydrogen chloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PHA‑767491 hydrochloride inhibits Cdc7 and CDK9 with low‑nanomolar potency (IC₅₀ = 10/34 nM), enabling coordinated suppression of DNA replication initiation and transcriptional elongation.

References : Sasi N. K. et al.: PLoS One., 9(11), e113300, 2014; Li W. et al.: Curr. Cancer Drug Targets., 15(3), 196-204, 2015; Erbayraktar Z. et al.: Cancer Cell Int., 16:88, 2016; Montagnoli A. et al.: Nat. Chem. Biol., 4(6), 357-65, 2008.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.