PHA-793887

SI-7808

PHA-793887, >98% (HPLC)

CAS No. : [718630-59-2]

IUPAC Name : N-(6,6-Dimethyl-5-(1-methylpiperidine-4-carbonyl)-1,4,5,6-tetrahydropyrrolo[3,4-c]pyrazol-3-yl)-3-methylbutanamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PHA‑793887 potently inhibits CDK2, CDK1, CDK4, and CDK9 with IC₅₀ values ranging from 8–138 nM and also targets GSK3β (IC₅₀= 79 nM). As an ATP‑competitive inhibitor, it provides a useful tool for probing CDK‑regulated cell‑cycle progression and GSK3β‑associated signaling pathways.

References : Brasca M. G. et al.: Bioorg. Med. Chem., 18(5), 1844-53, 2010; Locatelli G. et al.: Mol. Cancer Ther., 9(5), 1265-73, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.