Phenformin

SI-7897

Phenformin, >98% (HPLC)

CAS No. : [114-86-3]

Synonyms : Phenethylbiguanide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Phenformin inhibits complex I–driven mitochondrial respiration, triggering AMPK activation through elevated AMP/ATP ratios and suppressing mTOR signaling. This metabolic reprogramming induces apoptosis and autophagy while limiting cancer‑cell proliferation. Phenformin additionally targets cancer stem cells, contributing to its notable antitumor efficacy.

References : García Rubiño M. E. et al.: Int. J. Mol. Sci., 20(13), 3316, 2019; Alves-Silva A. B. et al.: Invest New Drugs., 40(3), 576-585, 2022; Hu. S. et al.: Mol. Med. Rep., 17(4), 6028-6032, 2018; Yendapally R. et al.: Drug. Dev. Res., 81(4), 390-401, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.