PI3K alpha inhibitor

SI-8135

PI3K alpha inhibitor, >98% (HPLC)

IUPAC Name : 1-Acryloyl-N-(2-(4-(4-(2-amino-4-(difluoromethyl)pyrimidin-5-yl)-6-morpholino-1,3,5-triazin-2-yl)piperazin-1-yl)-2-oxoethyl)piperidine-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a small‑molecule PI3Kα inhibitor designed to selectively block PI3Kα‑driven oncogenic signaling. Its multi‑heterocyclic scaffold supports high‑affinity engagement of the PI3Kα catalytic site, making it a useful tool compound for studying PI3Kα‑dependent tumor growth, survival, and metabolic regulation.

References : Hartung V. I. et al.: J. Med. Chem., 66, 9297-9312, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.