PI3Kgamma inhibitor 5

SI-6908

PI3Kγ inhibitor 5, >98% (HPLC)

CAS No. : [2566569-31-9]

IUPAC Name : 2-Amino-5-(2-(1-cyclopropylethyl)-7-(difluoromethoxy)-1-oxoisoindolin-5-yl)-N-(4-hydroxy-4-methylcyclohexyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : This is a highly potent, isoform‑selective PI3Kγ inhibitor was discovered through X‑ray, docking, and SAR optimization of amide and isoindolinone substituents. This (compound 56) showed strong PI3Kγ inhibition and induced a marked immune response by elevating pro‑inflammatory cytokine gene expression in M1 macrophages.

References : Mata G. et al.: J. Med. Chem., 65(2), 1418-1444, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.