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Pioglitazone EP impurity A

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SL-4374

Pioglitazone EP impurity A, >98%

CAS No. : [625853-74-9]

Synonyms : 5-Hydroxy pioglitazone impurity ; Pioglitazone 5-hydroxy metabolite

IUPAC Name : 5-(4-(2-(5-Ethylpyridin-2-yl)ethoxy)benzyl)-5-hydroxythiazolidine-2,4-dione

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Chemical Properites
Mol. Formula :
C19H20N2O4S
Mol. Weight :
372.44
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Pioglitazone (Pioglitazone EP impurity A), which is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes.

References : Jaakkola T. et al.: Basic Clin Pharmacol Toxicol., 99(1), 44-51, 2006; Shiomi T. et al.: Circulation. 106(24), 3126-3132, 2002; Dehmer T. et al.: J Neurochem, 88(2), 494-501, 2004; Breidert T. et al.: J. Neurochem 82(3), 615-624, 2002; Heneka M. T. et al.: Brain, 128(Pt 6), 1442-1453, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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