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Pioglitazone (M-III)

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SL-4370

Pioglitazone (M-III), >98%

CAS No. : [146062-45-5]

Synonyms : Pioglitazone metabolite (M-III); Keto pioglitazone (M-III)

IUPAC Name : 5-(4-(2-(5-Acetylpyridin-2-yl)ethoxy)benzyl)thiazolidine-2,4-dione

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Chemical Properites
Mol. Formula :
C19H18N2O4S
Mol. Weight :
370.42
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a metabolite of Pioglitazone, which is a selective peroxisome proliferator-activated receptor-gamma (PPARγ) agonist, used to treat diabetes.

References : Jaakkola T. et al.: Basic Clin Pharmacol Toxicol., 99(1), 44-51, 2006; Shiomi T. et al.: Circulation. 106(24), 3126-3132, 2002; Dehmer T. et al.: J Neurochem, 88(2), 494-501, 2004; Breidert T. et al.: J. Neurochem 82(3), 615-624, 2002; Heneka M. T. et al.: Brain, 128(Pt 6), 1442-1453, 2005.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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