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CAS No. : [2448-68-2]
Synonyms : Floropipamide dihydrochloride; McN-JR 3345 dihydrochloride; R-3345 dihydrochloride
IUPAC Name : 1'-(4-(4-Fluorophenyl)-4-oxobutyl)-[1,4'-bipiperidine]-4'-carboxamide dihydrochloride
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 250MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 500MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C21H30FN3O2 • 2HCl | Mol. Weight : 448.4 |
Appearance : Off-white solid | Melting Point : Not available |
Solubility : MeOH | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Pipamperone dihydrochloride is a butyrophenone derivative that serves as a high-affinity antagonist for the 5-HT2A receptor (pKi=8.2) and D4 receptor (pKi=8.0), while exhibiting low-affinity antagonism at the D2 receptor (pKi=6.7). By modulating neurotransmitter activity, pipamperone demonstrates antipsychotic effects. Pipamperone dihydrochloride is utilised in research focused on mental health conditions, including autism-related behavioural disorders and Alzheimer's disease.
References : Oekelen D. V. et al.: Eur. J. Pharmacol., 425(1), 21-32, 2001; Petrosino B. et al.: European Psychiatry 33(S1), S549-S549, 2016; Kamp D. et al.: Ther Adv Psychopharmacol., 6(1), 55-57, 2016.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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