Piperidine-GNE-049-N-Boc

SI-6897

Piperidine-GNE-049-N-Boc, >98% (HPLC)

CAS No. : [1936431-36-5]

IUPAC Name : tert-Butyl 3-(7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-1-(piperidin-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridine-5-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Piperidine‑GNE‑049‑N‑Boc serves as the CBP‑targeting warhead used to assemble the PROTAC degrader dCBP‑1. The resulting heterobifunctional molecule selectively degrades p300/CBP, enabling precise modulation of CBP/p300‑dependent transcriptional programs.

References : Vannam R. et. al.: Cell Chem. Biol., S2451-9456(20), 30513-4, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.