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Piragliatin

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SI-7724

Piragliatin, >98% (HPLC)

CAS No. : [625114-41-2]

Synonyms : RO-4389620

IUPAC Name : (R)-2-(3-Chloro-4-(methylsulfonyl)phenyl)-3-((R)-3-oxocyclopentyl)-N-(pyrazin-2-yl)propanamide

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Chemical Properites
Mol. Formula :
C19H20ClN3O4S
Mol. Weight :
421.9
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Piragliatin activates glucokinase, resulting in decreased hepatic glucose production, enhanced β‑cell function, and increased glucose uptake. This coordinated metabolic response lowers blood glucose and supports its antidiabetic activity.

References : Bonadonna R. C. et al.: J. Clin. Endocrinol. Metab., 95(11), 5028-36, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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