Pirtobrutinib

SI-7564

Pirtobrutinib, >98% (HPLC)

CAS No. : [2101700-15-4]

Synonyms : LOXO-305

IUPAC Name : (S)-5-Amino-3-(4-((5-fluoro-2-methoxybenzamido)methyl)phenyl)-1-(1,1,1-trifluoropropan-2-yl)-1H-pyrazole-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Pirtobrutinib selectively and reversibly inhibits BTK, including C481 mutant variants associated with resistance to covalent BTK inhibitors. It produces strong antitumor responses in BTK‑dependent lymphoma models and exhibits remarkable kinase selectivity (>300‑fold vs. 370 kinases) with minimal off‑target activity.

References : Gomez E. B. et al.: Blood, 134(1), 4644, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.