PKI-402

SI-7750

PKI-402, >98% (HPLC)

CAS No. : [1173204-81-3]

IUPAC Name : 1-(4-(3-Ethyl-7-Morpholino-3H-[1,2,3]triazolo[4,5-d]pyrimidin-5-yl)phenyl)-3-(4-(4-methylpiperazine-1-carbonyl)phenyl)urea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PKI‑402 inhibits PI3Kα, PI3Kβ, PI3Kδ, PI3Kγ, and mTOR with IC₅₀ values of 2–16 nM in a reversible, ATP‑competitive manner and retains potency against PI3K‑α mutants. Its dual PI3K/mTOR inhibition profile supports its use in studies of growth, survival, and metabolic signaling pathways.

References : Mallon R. et al.: Mol. Cancer Ther., 9(4), 976-84, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.