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Plazomicin

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SI-5224

Plazomicin, >98% (HPLC)

CAS No. : [1154757-24-0]

IUPAC Name : (S)-4-Amino-N-((1R,2S,3S,4R,5S)-5-amino-4-(((2S,3R)-3-amino-6-(((2-hydroxyethyl)amino)methyl)-3,4-dihydro-2H-pyran-2-yl)oxy)-2-(((2R,3R,4R,5R)-3,5-dihydroxy-5-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-3-hydroxycyclohexyl)-2-hydroxybutanamide

Price And Availability
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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
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25MGRequest A Quote
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50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Note: Plazomicin is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C25H48N6O10
Mol. Weight :
592.69
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Plazomicin is a next-generation aminoglycoside that has been designed as an antibiotic to avoid resistance through aminoglycoside-modifying enzymes. Plazomicin demonstrates high activity against the Enterobacteriaceae including extended spectrum beta lactamase and most carbapenemase producers, and can be useful in treating complicated urinary tract infections (cUTIs) and acute pyelonephritis.

References : Eljaaly K. et al.: Drugs 79(3), 243-269, 2019; Abdul-Mutakabbir J.C. et al.: Infect Dis Ther., 8(2), 155-170, 2019; Shaeer K. M. et al.: Pharmacotherapy 39(1), 77-93, 2019; McCarthy M. W. et al.: Drugs Today (Barc) 54(9), 513-518, 2018; Karaiskos I. et al.: Expert Opin Investig Drugs 24(11), 1501-11, 2015; Zhanel G. G. et al.: Expert Rev Anti Infect Ther., 10(4), 459-73, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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