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Pleconaril-d4

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SI-6573

Pleconaril-d4, >98% (HPLC)

CAS No. : [2749329-20-0]

Synonyms : VP-63843-d4; Win-63843-d4

IUPAC Name : 3-(3,5-Dimethyl-4-(3-(3-methylisoxazol-5-yl)propoxy-1,1,2,2-d4)phenyl)-5-(trifluoromethyl)-1,2,4-oxadiazole

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Chemical Properites
Mol. Formula :
C18H14D4F3N3O3
Mol. Weight :
385.38
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Pleconaril‑d4 is a deuterium-labelled version of Pleconaril. This can be used as an analytical labelled reference standard. Pleconaril targets a conserved hydrophobic pocket within the picornavirus capsid, interfering with attachment and uncoating steps essential for infection. Its broad activity profile makes it a valuable tool for investigating rhinovirus and enterovirus biology.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Benschop K. S. et al.: J. Gen. Virol., 96(3), 571-9, 2015; Lacroix C. et al.: Virol. J., 12, 106, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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