PNU-120596

SI-5670

PNU-120596, >98% (HPLC)

CAS No. : [501925-31-1]

MDL No. : MFCD00095313

Synonyms : NSC 216666

IUPAC Name : 1-(5-Chloro-2,4-dimethoxyphenyl)-3-(5-methylisoxazol-3-yl)urea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
1G	Request A Quote		Back Order	Estimated to ship on 04 October 2026
5G	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : PNU-120596 is a potent and selective α7 nAChR positive allosteric modulator (PAM) with an EC50 of 216 nM. PNU-120596 is inactive against α4β2, α3β4, and α9α10 nAChRs. PNU-120596 has the potential for psychiatric and neurological disorders research.

References : Hurst R. S. et al.: J. Neurosci., 25(17), 4396-4405, 2005; Barron S. C. et al.: Mol Pharmacol., 76(2), 253-263, 2009; Munro G. et al.: Br. J. Pharmacol., 167(2), 421-35, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.